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Free Medical Terminology Practice

Medical Prefix and Suffix Practice

📖 12 minute read • Updated July 2026 • Free Study Guide

Practice medical prefixes, suffixes, root words, and word breakdowns so long medical terms become easier to understand.

Built for nursing students, TEAS learners, anatomy students, allied health programs, medical assistant students, CBET learners, EMT learners, and early healthcare learners.

Prefix Beginning of word
Root Main meaning
Suffix Ending of word
Practice Active recall
Jump To

Why Medical Prefix and Suffix Practice Matters

Medical terminology becomes much easier when you stop trying to memorize every term as a separate definition. Instead, focus on the parts that make up the word.

Prefixes, suffixes, and roots act like building blocks. Once you understand those building blocks, you can decode unfamiliar words faster and with more confidence.

This matters for nursing, TEAS, anatomy, allied health, medical assisting, CBET, EMT, paramedic, and early healthcare learning because healthcare language repeats the same word parts again and again.

📖 Need a definition? As you learn prefixes, suffixes, and root words, look up unfamiliar terms in the MedSkillBuilder Medical Dictionary. Search hundreds of medical definitions, abbreviations, anatomy terms, lab values, procedures, medications, diseases, and healthcare vocabulary written in plain English.
Quick example: If you know hyper- means high, kal refers to potassium, and -emia means blood condition, you can work out that hyperkalemia means high potassium in the blood.
Prefix Beginning
Example: hyper-
Root Main meaning
Example: cardi
Suffix Ending
Example: -itis
Meaning Decode the full word

How to Use This Practice Page

Use this page as a quick review and practice guide. Start with common word parts, study the examples, then move into interactive medical terminology practice.

This page works best when you actively quiz yourself instead of only reading. Say meanings out loud, cover answers, and break terms into smaller pieces.

  1. Review a small group of prefixes or suffixes.
  2. Say the meaning out loud.
  3. Look at the example term.
  4. Break the term into parts.
  5. Practice the same terms again later without looking.
  6. Use the interactive terminology tab when you are ready for more repetition.
Do not try to memorize every medical word in one sitting. Learn patterns first. Then add more terms over time.

Common Medical Prefixes to Practice First

Prefixes usually appear at the beginning of a term. They often describe speed, amount, location, time, number, direction, or relationship.

a- / an-
without, absence of
apnea = absence of breathing

Use when something is missing or absent.

anti-
against
antibiotic = against bacteria

Often used for medications or defenses.

auto-
self
autoimmune = immune response against self

Common in disease-process terms.

bi-
two
bilateral = both sides

Think two sides or two parts.

brady-
slow
bradycardia = slow heart rate

High-yield vital sign prefix.

contra-
against, opposite
contraindication = reason not to use

Important in medication safety.

dys-
bad, difficult, abnormal
dyspnea = difficult breathing

Common in symptom terms.

endo-
within, inside
endoscopy = visual exam inside the body

Think entering inside.

epi-
upon, above
epidermis = outer layer of skin

Often means upon a surface.

eu-
normal, good
eupnea = normal breathing

Useful for respiratory terminology.

ex- / extra-
outside
extracellular = outside the cell

Opposite of intra- in many terms.

hemi-
half
hemiplegia = paralysis of one side

Often used in neuro terms.

hyper-
high, above normal
hypertension = high blood pressure

Compare carefully with hypo-.

hypo-
low, below normal
hypoglycemia = low blood sugar

Compare carefully with hyper-.

inter-
between
intercostal = between the ribs

Interstate goes between states.

intra-
within
intravenous = within a vein

Intra means inside one thing.

macro-
large
macrocyte = large cell

Opposite of micro-.

micro-
small
microscope = instrument to view small things

Opposite of macro-.

neo-
new
neoplasm = new growth

Common in disease terms.

oligo-
few, little
oliguria = low urine output

Used for low amount but not always zero.

pan-
all
pancytopenia = low counts of all blood cells

Think all or total.

peri-
around
pericardium = around the heart

Perimeter goes around.

poly-
many, much
polyuria = excessive urination

Often means too much.

post-
after
postoperative = after surgery

Time-related prefix.

pre-
before
prenatal = before birth

Time-related prefix.

retro-
behind, backward
retroperitoneal = behind the peritoneum

Used in anatomy locations.

sub-
under, below
subcutaneous = under the skin

Common medication route.

supra-
above
suprapubic = above the pubic area

Location prefix.

tachy-
fast
tachypnea = fast breathing

High-yield vital sign prefix.

trans-
across, through
transdermal = through the skin

Common medication delivery term.

Common Medical Suffixes to Practice First

Suffixes usually appear at the end of a term. They often describe a condition, procedure, test, record, disease process, or specialty.

-algia
pain
neuralgia = nerve pain

Ask: where is the pain?

-cele
hernia, swelling
cystocele = bladder herniation

Common in anatomy terms.

-centesis
surgical puncture
thoracentesis = puncture of chest space

Procedure suffix.

-cyte
cell
leukocyte = white blood cell

CBC-related term.

-ectomy
surgical removal
appendectomy = removal of appendix

Procedure suffix.

-emia
blood condition
anemia = blood condition

Often lab-related.

-genic
producing, caused by
iatrogenic = caused by medical treatment

Cause-related suffix.

-gram
record, image
electrocardiogram = heart electrical record

Result or tracing.

-graphy
recording process
radiography = imaging process

Process of recording.

-iasis
abnormal condition
cholelithiasis = gallstone condition

Condition suffix.

-itis
inflammation
dermatitis = skin inflammation

Very high-yield suffix.

-lysis
breakdown, destruction
hemolysis = breakdown of blood cells

Cell and lab term.

-megaly
enlargement
cardiomegaly = enlarged heart

Size-related suffix.

-oma
mass, tumor
hematoma = collection of blood

May be benign or malignant depending term.

-osis
abnormal condition
cyanosis = bluish discoloration

Broad condition suffix.

-ostomy
surgically created opening
colostomy = opening into colon

Procedure suffix.

-otomy
cutting into
tracheotomy = cutting into trachea

Different from -ectomy.

-pathy
disease, disorder
neuropathy = nerve disorder

Disease-process suffix.

-penia
deficiency, low amount
leukopenia = low white blood cells

CBC/lab suffix.

-pexy
surgical fixation
nephropexy = kidney fixation

Procedure suffix.

-phagia
eating, swallowing
dysphagia = difficulty swallowing

GI/safety term.

-phasia
speech
aphasia = loss of speech ability

Neuro term.

-plasia
formation, growth
hyperplasia = excessive growth

Cell growth term.

-plasty
surgical repair
angioplasty = vessel repair/opening

Procedure suffix.

-pnea
breathing
apnea = absence of breathing

Respiratory suffix.

-rrhea
flow, discharge
diarrhea = abnormal flow/discharge

GI/common symptom suffix.

-scopy
visual examination
endoscopy = visual exam inside body

Procedure suffix.

-stasis
stopping, controlling
hemostasis = stopping bleeding

Safety and procedure term.

-uria
urine condition
polyuria = excessive urination

GU/lab suffix.

Root Words That Make Prefixes and Suffixes Easier

Root words carry the main meaning of a medical term. When you combine roots with prefixes and suffixes, you can decode many healthcare words faster.

Root WordMeaningExamplePlain MeaningHealthcare Connection
cardi / cardio heart cardiology heart specialty EKG, heart sounds, chest pain
angi / vas vessel angioplasty vessel repair circulation and blood pressure
arteri artery arteriosclerosis artery hardening vascular disease
ven / phleb vein phlebitis vein inflammation IV and circulation
pulmon / pneumo lung or air pneumonia lung infection oxygen and breath sounds
rhin nose rhinitis nose inflammation ENT assessment
laryng larynx laryngitis larynx inflammation airway and voice
trache trachea tracheotomy cutting into trachea airway management
gastr stomach gastritis stomach inflammation GI assessment
enter intestine enteritis intestinal inflammation GI terms
col / colon colon colostomy opening into colon GI surgery
hepat liver hepatitis liver inflammation metabolism and labs
chole bile/gallbladder cholecystectomy gallbladder removal GI surgery
nephr / ren kidney nephrology kidney specialty BUN, creatinine, GFR
cyst bladder cystitis bladder inflammation urinary symptoms
neur / neuro nerve neuropathy nerve disorder neuro assessment
encephal brain encephalitis brain inflammation mental status
myel spinal cord or bone marrow myelopathy spinal cord disorder neuro/CBC context
oste / osteo bone osteoporosis bone condition skeletal system
arthr joint arthritis joint inflammation mobility and pain
my / myo muscle myalgia muscle pain muscle anatomy
derm / dermat skin dermatitis skin inflammation skin assessment
hem / hemat blood hematology study of blood CBC and bleeding
leuk white leukocyte white blood cell infection and CBC
erythr red erythrocyte red blood cell oxygen transport
thromb clot thrombosis clot condition vascular safety
glyc sugar hypoglycemia low blood sugar diabetes terminology
cyt cell cytology study of cells labs and pathology

When you encounter a root word you do not recognize, search the Medical Dictionary for a complete definition and related healthcare terms before returning to practice.

Medical Word-Building Examples

One of the best ways to learn terminology is to see how the parts come together inside full words.

Medical TermHow It Breaks DownPlain MeaningWhat to Notice First
Bradycardia brady + cardia Slow heart rate brady- = slow
Tachypnea tachy + pnea Fast breathing tachy- = fast
Hypoglycemia hypo + glyc + emia Low blood sugar hypo- = low
Hyperkalemia hyper + kal + emia High potassium in blood hyper- = high
Pericarditis peri + card + itis Inflammation around the heart -itis = inflammation
Neuropathy neuro + pathy Nerve disease or disorder -pathy = disease/disorder
Hepatomegaly hepato + megaly Enlarged liver -megaly = enlargement
Subcutaneous sub + cutaneous Under the skin sub- = under
Electrocardiogram electro + cardio + gram Record of heart electrical activity -gram = record
Endoscopy endo + scopy Visual examination inside body endo- = inside
Leukopenia leuko + penia Low white blood cells -penia = deficiency
Hemolysis hemo + lysis Breakdown of blood cells -lysis = breakdown
Dysphagia dys + phagia Difficulty swallowing dys- = difficult
Colostomy colo + stomy Surgical opening into colon -stomy = opening
Osteoporosis osteo + porosis Porous/weak bone condition osteo = bone
What to notice first: If the word ends in -itis, think inflammation. If it ends in -ectomy, think removal. If it begins with hyper- or hypo-, look for high or low.

Commonly Confused Medical Prefixes

Many learners miss terminology questions because two prefixes look or sound similar. Use this table to separate the high-yield pairs.

PrefixMeansOften Confused WithMemory Tip
hyper- high hypo- Hyper people are high energy.
hypo- low hyper- Hypo sounds like low.
brady- slow tachy- Brady means slow pace.
tachy- fast brady- Tachometer reminds you of speed.
endo- inside epi- Endo means entering inside.
peri- around intra- Perimeter goes around.
intra- within inter- Intravenous is within a vein.
inter- between intra- Interstate goes between states.
sub- under supra- Submarine goes under.
supra- above sub- Supra means above.

Memory Tricks for Faster Recall

Hyper = High

Think of someone who is hyper with high energy.

Hypo = Low

Think of a low battery warning. Hypo means low or below normal.

Brady = Slow

Picture someone taking a slow walk. Brady means slow.

Tachy = Fast

Think of a tachometer measuring speed. Tachy means fast.

-itis = Inflammation

When a word ends in -itis, ask: what body part is inflamed?

-ectomy = Removal

Appendectomy, tonsillectomy, and mastectomy all involve removal.

-gram = Record

A gram is the record or picture, not necessarily the process.

-scopy = Look Inside

Scope means visual examination, like endoscopy or bronchoscopy.

Body System Practice Groups

Medical word parts become easier when you connect them to body systems instead of learning them as random vocabulary.

Cardiac and Circulation

  • cardio- = heart
  • bradycardia = slow heart rate
  • tachycardia = fast heart rate
  • angioplasty = vessel repair/opening
  • electrocardiogram = heart electrical record

Respiratory

  • pulmon- = lung
  • pneumo- = air/lung
  • tachypnea = fast breathing
  • dyspnea = difficult breathing
  • apnea = absence of breathing

Kidney and Urinary

  • nephr- = kidney
  • renal = kidney related
  • -uria = urine condition
  • polyuria = excessive urination
  • cystitis = bladder inflammation

Digestive

  • gastr- = stomach
  • enter- = intestine
  • hepat- = liver
  • colostomy = opening into colon
  • cholecystectomy = gallbladder removal

Neuro

  • neuro- = nerve
  • encephal- = brain
  • aphasia = loss of speech
  • neuropathy = nerve disorder
  • hemiplegia = paralysis of one side

Musculoskeletal

  • osteo- = bone
  • arthr- = joint
  • myo- = muscle
  • myalgia = muscle pain
  • osteoporosis = abnormal bone condition

Practice Questions

Try answering these before reading the answer. Active recall is what makes the word parts stick.

1. What does hyper- mean?

A. Low
B. High or above normal
C. Slow
D. Around



Answer: High or above normal
Hypertension means high blood pressure.

2. What does hypo- mean?

A. High
B. Low or below normal
C. Fast
D. Study of

Answer: Low or below normal
Hypoglycemia means low blood sugar.

3. What does -itis mean?

A. Surgical removal
B. Inflammation
C. Pain
D. Enlargement

Answer: Inflammation
Arthritis means joint inflammation.

4. What does bradycardia mean?

A. Fast heart rate
B. Slow heart rate
C. Low oxygen
D. High blood pressure

Answer: Slow heart rate
Brady- means slow and cardi relates to heart.

5. What does appendectomy mean?

A. Inflammation of appendix
B. Pain in appendix
C. Surgical removal of appendix
D. Study of appendix

Answer: Surgical removal of appendix
-ectomy means surgical removal.

6. Which suffix means pain?

A. -algia
B. -gram
C. -ectomy
D. -scopy

Answer: -algia
Myalgia means muscle pain.

7. What does subcutaneous mean?

A. Inside the vein
B. Under the skin
C. Around the heart
D. Above the stomach

Answer: Under the skin
Sub- means under and cutaneous relates to skin.

8. Which word means fast breathing?

A. Bradypnea
B. Tachypnea
C. Hypoxia
D. Cardiomegaly

Answer: Tachypnea
Tachy- means fast and -pnea relates to breathing.

9. Which suffix means record or image?

A. -itis
B. -gram
C. -plasty
D. -megaly

Answer: -gram
An electrocardiogram is a recorded tracing.

10. What does peri- mean?

A. Around
B. Within
C. Under
D. After

Answer: Around
Pericardium means around the heart.

11. What does -megaly mean?

A. Pain
B. Inflammation
C. Enlargement
D. Study of

Answer: Enlargement
Cardiomegaly means enlarged heart.

12. What does intra- mean?

A. Between
B. Within
C. Under
D. Around

Answer: Within
Intravenous means within a vein.

13. What does -stomy mean?

A. Inflammation
B. Surgical opening
C. Pain
D. Enlargement

Answer: Surgical opening
Colostomy is a surgically created opening.

14. Which term means inflammation around the heart?

A. Cardiology
B. Pericarditis
C. Cardiomegaly
D. Neuropathy

Answer: Pericarditis
Peri + card + itis = inflammation around the heart.

15. What does dysphagia mean?

A. Difficult breathing
B. Difficulty swallowing
C. Low blood sugar
D. Fast heart rate

Answer: Difficulty swallowing
Dys- means difficult and -phagia relates to swallowing/eating.

16. Which suffix means deficiency or low amount?

A. -penia
B. -oma
C. -scopy
D. -plasty

Answer: -penia
Leukopenia means low white blood cells.

17. Which root means kidney?

A. cardi
B. nephr
C. derm
D. gastr

Answer: nephr
Nephrology is the study/specialty of kidneys.

18. Which root means skin?

A. derm
B. hepat
C. neur
D. oste

Answer: derm
Dermatitis is inflammation of the skin.

19. What does tachycardia mean?

A. Slow breathing
B. Fast heart rate
C. Low heart rate
D. Pain in the heart

Answer: Fast heart rate
Tachy- means fast and cardia relates to heart.

20. What does -scopy mean?

A. Visual examination
B. Surgical removal
C. Pain
D. Blood condition

Answer: Visual examination
Endoscopy is a visual examination inside the body.

Where You'll See These on Exams

Medical prefixes, suffixes, and root words show up across healthcare learning. Even when an exam is not directly called a medical terminology exam, word parts often appear inside anatomy, vital signs, medication, lab value, and clinical scenario questions.

TEAS and Pre-Nursing

Helps with science vocabulary, anatomy terms, and unfamiliar healthcare words.

Nursing School

Supports clinical language, charting, medication terms, symptoms, and disease names.

Medical Assisting

Builds confidence with clinic vocabulary, body systems, procedures, and documentation.

EMT and Paramedic

Helps decode emergency terms involving breathing, circulation, trauma, and body systems.

CBET and Biomed

Strengthens healthcare language used around monitoring, equipment, and clinical environments.

Anatomy and Physiology

Connects roots and suffixes to organs, tissues, and system functions.

Printable Study Sheet Preview

Use this quick reference when you need a fast review before a quiz, class, or clinical skills session.

Frequently Asked Questions

Why is learning medical prefixes and suffixes important?

Medical prefixes and suffixes are the building blocks of clinical terminology. Knowing common word parts helps you decode unfamiliar terms in class, on exams, and in healthcare settings.

What medical prefixes should I learn first?

A strong starting group includes brady-, tachy-, hyper-, hypo-, peri-, endo-, epi-, sub-, inter-, intra-, pre-, post-, poly-, dys-, and a-.

What are common medical suffixes to study?

Frequently tested suffixes include -itis, -ectomy, -plasty, -oscopy, -ology, -pathy, -algia, -emia, -megaly, -gram, -graphy, -oma, and -osis.

How can I memorize medical word parts faster?

Use active recall, repeated review, memory tricks, and real examples. Practice matching prefixes and suffixes to their meanings and break larger medical terms into smaller parts.

What is the difference between a prefix, root word, and suffix?

A prefix appears at the beginning of a medical term, a root word carries the main meaning, and a suffix appears at the end. Together they help explain the meaning of medical terminology.

Are medical prefixes and suffixes useful for TEAS?

Yes. TEAS learners benefit from knowing medical word parts because anatomy, physiology, and healthcare vocabulary often use prefixes, suffixes, and root words.

Is this page only for nursing students?

No. It can help nursing students, TEAS learners, anatomy students, medical assistants, allied health students, CBET learners, EMT learners, and anyone starting healthcare vocabulary.